Stem Cell Therapy
Stem cell Therapy
Begin Your
Journey To The Best cell recovery
Stem cell supernatant intravenous drip is said to promote the recovery of damaged tissues and cells in the body, and is used for various purposes, ranging from improving non-specific symptoms to anti-aging care.
Please experience our cellular-level care approach.
Our clinic operates on a referral-only basis.
What is Stem Cell Supernatant Intravenous Drip?
When stem cells are cultured, the culture medium secretes a variety of growth factors and proteins. The liquid rich in these generated growth factors is then purified into the supernatant. Recent studies have shown that these growth factors and other bioactive substances secreted by stem cells can act on damaged cells, promoting tissue regeneration, and expectations for their effectiveness are growing.
The culture medium used to cultivate stem cells secretes active components such as cytokines.
The supernatant extracted from stem cells is rich in active components that stimulate cellular regeneration.
The difference between stem cell supernatant and stem cell therapy.
Quality Management
Stem cell therapy involves collecting your own cells, culturing, and administering them as a treatment. However, even when culturing your own damaged cells, the effectiveness may be limited, and achieving significant change can be challenging. Additionally, there is a risk of bacterial contamination during each culturing process, which has led to reported complications in some cases.
On the other hand, stem cell supernatant utilizes components secreted by stem cells, such as growth factors and exosomes, to activate your own stem cells and other cells. This approach is expected to improve cellular function and is considered to have a higher safety profile.
The quality of our clinic's stem cell supernatant.
Quality Management
AFRODE CLINIC offers treatment using human adipose-derived mesenchymal stem cell culture supernatant, manufactured at our partnered cell culture processing facility, made from pure, domestically produced Japanese materials.
Our stem cell culture supernatant is the only product in the world that is insured under product liability insurance (PL insurance) as a pharmaceutical product, ensuring its high quality.
Stem cell supernatant is still in the transitional phase of research, and it is generally said that manufacturing methods vary between culture facilities, leading to differences in efficacy. Our clinic’s product is made using unique raw materials and culturing techniques, with a focus on balancing the components and pursuing clinical results. Based on our clinical findings, we believe that our supernatant is more effective than others on the market, and research has shown improvements in various cases during the clinical trial phase.
Thorough Quality Control
"Proven safety" through four types of safety tests.
Human virus testing.
Real-time PCR testing.
We conduct testing for human viruses (HIV1, HIV2, HCV, HBV, HTLV1&2, Parvovirus B19) as recommended in the guidelines for the quality and safety of cell-processing pharmaceuticals. The test involves centrifuging the sample to collect cells, extracting nucleic acids using the NucleoSpin RNA kit with a simultaneous DNA/RNA extraction process, and determining the presence of the virus using reverse transcription/real-time PCR with primers/probe sets specific to each virus's sequence.
Sterility testing.
Gas measurement method / BacT/Alert method testing.
We conduct measurements for aerobic bacteria, such as molds, and anaerobic bacteria that do not require oxygen, which may proliferate during culturing. Using the BacT/Alert sterility testing device, the test sample is inoculated into the test medium and cultured under conditions of 32.7°C for 7 days. Sterility is determined based on bacterial growth. Additionally, as an inhibition confirmation test, the test sample and various standard bacteria are inoculated into the test medium and cultured under the same conditions. The growth of the standard bacterial species is confirmed, ensuring there is no inhibition.
Endotoxin testing.
Endosafe method testing.
Endotoxins are a type of pyrogen (fever-causing substance) with biological activities such as fever-inducing effects and lethal toxicity. The sample is added to the Endosafe-PTS cartridge JP, and measurement is performed using an endotoxin detection device. By using the endotoxin standard included in the cartridge as a reference, the recovery rate of the endotoxin standard and the endotoxin concentration in the sample are measured.
Mycoplasma contamination testing.
Real-time PCR testing.
Mycoplasma is the smallest microorganism capable of self-replication and is biologically classified as a bacterium. It is also known to cause diseases like pneumonia. Due to its small size and lack of a cell wall, it is difficult to observe. For detection, we use the MycoSEQ Mycoplasma Detection Kit to extract DNA from both the sample and a positive control DNA added to the sample. Then, we use mycoplasma-specific primers and real-time PCR to determine the presence of mycoplasma.
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Expected effects and symptoms that have shown improvement.
Vascular regeneration and angiogenesis effects.
Cell repair and regeneration effects.
Anti-inflammatory effects.
Reactive oxygen species (ROS) removal effects.
Immune modulation effects.
Beautifying effects.
Bone, muscle, and joint symptoms.
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Relief of joint pain
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Promotion of muscle soreness recovery
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Reduction of nerve pain and numbness
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Suppression of inflammation after injury or exercise
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Improvement in flexibility
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Protection of joint function due to aging
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Relief from lower back pain, shoulder stiffness, and similar conditions
Improvement in mental health.
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Stress reduction
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Relaxation effects
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Relief from anxiety and depressive symptoms
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Improved concentration
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Balancing the body and mind through improved sleep
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Relief from mental fatigue
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Stabilization of hormone balance
Systemic symptoms.
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Chronic Fatigue Syndrome
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Immune function
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Headaches
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Fatigue
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Dizziness and lightheadedness
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Sleep disorders
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Rheumatic diseases
Skin symptoms.
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Wrinkles and sagging
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Pore reduction and skin texture improvement
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Dry skin and sensitive skin
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Vitiligo (white spots)
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Skin irritation
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Dark spots, wrinkles, and dullness
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Improvement of hair loss and thinning hair
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Vascular symptoms.
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Arrhythmia
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Peripheral circulation disorders
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Myocardial infarction
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Arteriosclerosis
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Cerebral infarction
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Relief from cold sensitivity
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Prevention of varicose veins
Post-surgery and hair loss support.
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Promotion of post-surgery recovery
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Acceleration of wound healing
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Improvement of hair loss
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Stimulation of hair follicles for hair growth
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Prevention of hair shedding
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Anti-aging care for the neck and hands
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Improvement of liver function and detoxification effects
Dr. Shotaro Michishita
AFRODE CLINIC provides efficient, drug-free recovery and preventive healthcare, centered on medical expertise, for individuals such as business executives and public figures who experience daily physical and mental strain. Our goal is to establish this field as a new medical option and integrate it into everyday life.
evidence
Nerve regeneration.
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Stem cell supernatant exhibits nerve regeneration effects, helping alleviate pain, dysfunction, and muscle atrophy associated with nerve damage.
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When nerve damage occurs, stem cell supernatant helps prevent muscle atrophy and shifts the microenvironment from fibrosis to a self-regenerating state.